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Variability in drug therapy description, estimation, and control : a Sandoz workshop by

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Published by Raven Press in New York .
Written in English


  • Drugs -- Dose-response relationship -- Congresses,
  • Pharmacokinetics -- Congresses,
  • Biochemical variation -- Congresses,
  • Chemotherapy -- Congresses,
  • Dose-Response Relationship, Drug -- congresses,
  • Drugs -- administration & dosage -- congresses,
  • Drugs -- metabolism -- congresses,
  • Drug Therapy -- congresses

Book details:

Edition Notes

Statementeditors, Malcolm Rowland, Lewis B. Sheiner, Jean-Louis Steimer.
ContributionsRowland, Malcolm., Sheiner, Lewis B., Steimer, Jean-Louis., Sandoz AG.
LC ClassificationsRM301.8 .V37 1985
The Physical Object
Paginationxxi, 246 p. :
Number of Pages246
ID Numbers
Open LibraryOL3021699M
ISBN 100881670804
LC Control Number85001888

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  Variability in Human Drug Response Description. Variability in Human Drug Response examines why individual patients differ significantly in their response Table of Contents. Details. About the Author. Review's title & body can't be empty Question's body can't be empty Please enter a star rating Book Edition: 1. Variability in Drug Therapy Description, Estimation, and Control A Sandoz Workshop Editors Malcolm Rowland, Ph.D. Lewis B. Sheiner, M.D. Professor of Pharmacy Professor of Laboratory Medicine and Department of Pharmacy of Medicine University of Manchester Departments of Laboratory Medicine Manchester, United Kingdom and of Medicine School of. Individualized Drug Therapy for Patients: Basic Foundations, Relevant Software and Clinical Applications focuses on quantitative approaches that maximize the precision with which dosage regimens of potentially toxic drugs can hit a desired therapeutic goal. This book highlights the best methods that enable individualized drug therapy and provides specific examples on how to incorporate these . drug therapy Drug Metabolism and Variability among Patients in Drug Response Grant R. Wilkinson, Ph.D., From the Department of Pharmacology, Vanderbilt University, Nashville. Address reprint requests to Dr. Wilkinson at the Department of Pharmacology, Vanderbilt University, Robinson Research Bldg., Nashville, TN , or at grant.

Purchase Therapeutic Drug Monitoring - 1st Edition. Print Book & E-Book. ISBN , Variability exists in both pharmacokinetics and pharmacodynamics. For a typical drug, one standard deviation in the values observed for bioavailability (F), clearance (CL) and volume of distribution (Vd) would be about 20%, 50% and 30% respectively. This book will be of immense value for students to develop themselves as the meritorious & motivated candidates for admission to post graduate courses like M.D., M.S. & I compliment the author for his pains-taking efforts in mobilizing a very large number of good MCQs from a vast. drug therapy. The development of strong correlations between drug concentrations and their pharmacologic responses has enabled clinicians to apply pharmacoki-netic principles to actual patient situations. A drug’s effect is often related to its concentration at the site of action, so it would be useful to monitor this concentration.

Individual variation in drug response Prescribers have numerous sources of guidance about how to use drugs appropriately (e.g. dose, route, frequency, duration) for many conditions. However, this advice is based on average dose–response data derived from observations in many individuals. The term case management has appeared in social services literature more than times in the last 30 years, referring to everything from the routing of court dockets through the judicial system to the medical management of a hospitalized patient's care. This TIP uses the term to refer to interventions designed to help substance abusers access needed social services.   Variability in the response to drugs is due to three principal components—the disease, the responsiveness of tissues, and the concentration of the drug at its site of action (as reflected by its plasma concentration). Genre/Form: Conference papers and proceedings Congress Congresses Congrès: Additional Physical Format: Online version: Variability in drug therapy. New York: Raven Press, ©